Symptomatic SARS-COV-2 Re-infection: Healthcare Workers and Immunosuppressed Individuals at High Risk, Researchers Say

Knowledge regarding factors predicting the SARS-COV-2 reinfection risk is scarce and it has major implications in public health policies, say Murillo-Zamora, et al. (2021) who aimed to identify factors associated with the risk of symptomatic SARS-COV-2 reinfection.

The researchers conducted a nationwide retrospective cohort study and 99,993 confirmed cases of COVID-19 were analyzed.

The overall risk of reinfection (28 or more elapsed days between both episodes onset) was 0.21% (incidence density, 2.5 reinfections per 100,000 person-days) and older subjects and those with the mild primary disease were at reduced risk of the event. Healthcare workers and immunosuppressed or renal patients had at greater risk of SARS-COV-2 reinfection.

If replicated in other populations, the researchers say these results may be useful to prioritize efforts focusing on the reduction of SARS-COV-2 spread and the related burden.

Reference: Murillo-Zamora E, et al. Symptomatic SARS-COV-2 reinfection: healthcare workers and immunosuppressed individuals at high risk. BMC Infectious Diseases. Vol. 21, article number 923, 2021.