This special issue of Healthcare Hygiene magazine presents key highlights shared by some of the world’s best and brightest minds who fuel the research and advance the evidence-based agendas of the infection prevention, healthcare epidemiology and public health communities. Reporting on the Decennial Day presentations that were held April 12, 2021, this special edition provides an executive reader of the perspectives and information that emerged from this digital event, part of SHEA’s spring conference. To access this special edition, CLICK HERE.