Babies With COVID-19 Tend to Have Mild Illness, Mostly With Fever

A report from Ann & Robert H. Lurie Children's Hospital of Chicago shows that infants under 90 days of age who tested positive for COVID-19 tend to be well, with little or no respiratory involvement. Fever was often found to be the primary or only symptom. Findings were published in the Journal of Pediatrics.

"While there is limited data on infants with COVID-19 from the United States, our findings suggest that these babies mostly have mild illness and may not be at higher risk of severe disease as initially reported from China." says lead author Leena B. Mithal, MD, MSCI, pediatric infectious diseases expert from Lurie Children's and assistant professor of pediatrics at Northwestern University Feinberg School of Medicine. "Most of the infants in our study had fever, which suggests that for young infants being evaluated because of fever, COVID-19 may be an important cause, particularly in a region with widespread community activity. However, evaluation for bacterial infection in young infants with fever remains important."

The study included 18 infants, none with a significant medical history. Of the 50 percent of these infants who were admitted to the hospital's general inpatient service, none required oxygen, respiratory support, or intensive care. Indications for admission were mainly clinical observation, monitoring of feeding tolerance, and ruling-out bacterial infection with empiric intravenous antibiotics in infants younger than 60 days. Of the infants admitted to the hospital, six out of nine had gastrointestinal (GI) symptoms (poor feeding, vomiting and diarrhea). Upper respiratory tract symptoms of cough and congestion preceded onset of GI symptoms. Young infants also had notably high viral loads in their nasal specimens despite mild clinical illness.

"It is unclear whether young infants with fever and a positive test for SARS-CoV-2 require hospital admission," says Dr. Mithal. "The decision to admit to the hospital is based on age, need for preemptive treatment of bacterial infection, clinical assessment, feeding tolerance, and adequacy of follow-up." There may be opportunities to utilize rapid SARS-CoV-2 testing to determine disposition of clinically well infants with fever."

Mithal and colleagues (Machut, Muller, and Kociolek) also observed an overrepresentation of Latinx ethnicity among their sample of infants with COVID-19 (78 percent). At the height of the COVID-19 pandemic in Chicago, over 40 percent of cases were in individuals of Latinx ethnicity.

"Although we expected that there would be many infants of Latinx ethnicity with COVID-19, there may be additional factors contributing to the disproportionate majority of Latinx cases we observed in this age group," says Mithal. "Access to sick-visit care in some primary care pediatric offices has been limited, with practices referring symptomatic children to the emergency department. Limited access to telemedicine care also may be a factor. Finally, there may be a greater likelihood of exposure with extended family living in the home or family members working outside the home during this pandemic."

Source: Ann & Robert H. Lurie Children's Hospital of Chicago

7 Comments on "Babies With COVID-19 Tend to Have Mild Illness, Mostly With Fever"

  1. 852838 616139When I originally commented I clicked the “Notify me when new comments are added” checkbox and now each time a comment is added I get several e-mails with the same comment. Is there any way you can remove me from that service? Thank you! 664188

  2. 231698 64529I got what you mean , saved to my bookmarks , very good website . 718508

  3. 451317 139159A actually fascinating examine, I could not concur entirely, but you do make some extremely valid points. 1824

  4. 950247 423876I like you blog (dsol, je suis francais, je parle mal anglais) 707003

  5. 788457 911502Hello! I just now would like to supply a massive thumbs up for any amazing information you can have here within this post. We are coming back to your weblog post for further soon. 692916

  6. 119244 194788hey there i stumbled upon your internet site looking about the internet. I wanted to say I enjoy the look of items around here. Maintain it up will save for confident. 444965

  7. 488207 643770You Finally want the respect off your family and buddies? 684066

Leave a comment

Your email address will not be published.


*