Femoral Site of Catheter Insertion Associated With a Higher Rate of Bloodstream Infection

Placement of central-venous catheters (CVCs) is an essential practice in the management of hospitalized patients, however, insertion at the commonly used sites has often the potential of inducing major complications. Nevertheless, the impact of specific site central line catheter insertion on catheter-associated bloodstream infections (CLABSIs) has not been clarified yet in the literature.

The aim of the study by Pitiriga, et al. (2020) was to compare CLABSIs and catheter colonization rates among the three catheter insertion sites: subclavian (SC), internal jugular (IJ) and femoral (FEM) in hospitalized patients. Moreover, to analyze the distribution of pathogens and their antimicrobial resistance profiles at these three sites, concurrently.

The researchers performed a retrospective analysis of data collected prospectively from all catheterized patients at a tertiary care Greek hospital from May 2016 to May 2018. Data was collected on 1414 CVCs and 13,054 CVC-days.

Τhe incidence of CLABSIs among the three sites was as follows: SC:5.1/1000 catheter/days, IJ: 3.73/1000 catheter/days and FEM: 6.93/1000 catheter/days (p = 0.37). The incidence of colonization was as follows: SC:13.39/1000 catheter/days; IJ:7.34/ 1000 catheter/days; FEM:22.91/1000 catheter/days (p = 0.009). MDROs predominated in both CLABSIs and tip colonizations (59.3 and 61%, respectively) with Acinetobacter baumanii being the predominant pathogen (16/59, 27.1% and 44/144, 30.5%, respectively). The incidence of CLABSIs due to multidrug-resistant organisms (MDROs) was as follows: SC:3.83/1000 catheter days; IJ:1.49/1000 catheter days; FEM:5.86/1000 catheter days (p = 0.04). The incidence of tip colonization by MDROs among the 3 sites was as follows: SC:8.93/1000 catheter/days; IJ:4.48/1000 catheter/days; FEM:12.79/1000 catheter/days (p = 0.06). There was no significant difference in the type of pathogen isolated among site groups for both CLABSIs and tip colonizations.

The researchers conclude that FEM site of catheter insertion was associated with a higher rate of bloodstream infection and catheters’ colonization compared to IJ and SC sites. Furthermore, this survey highlights the changing trend of the distribution of frequent pathogens and resistance patterns towards MDR Gram-negative pathogens, underscoring the need for consistent monitoring of antimicrobial resistance patterns of these specific infections.

Reference: Pitiriga V, Kanellopoulos P, et al. Central venous catheter-related bloodstream infection and colonization: the impact of insertion site and distribution of multidrug-resistant pathogens. Antimicrobial Resistance & Infection Control. Vol. 9, No. 189. 2020.


7 Comments on "Femoral Site of Catheter Insertion Associated With a Higher Rate of Bloodstream Infection"

  1. 439839 144828My California Weight Loss diet invariably is an cost effective and versatile staying on your diet tv show made for people who locate themselves preparing to drop extra pounds and furthermore ultimately keep a a lot healthier habits. la weight loss 416281

  2. 683080 404495I came across this great from you out of sheer luck and never believe lucky enough to say also credit you for any job well done. 105939

  3. 120813 884763I like this weblog really a lot, Its a rattling good billet to read and discover info . 533980

  4. 636637 819226This internet internet site is my aspiration, extremely exceptional style and Perfect articles. 119438

  5. 37452 513710Bookmarked your great web site. Fabulous work, special way with words! 118559

  6. 985767 438333Thank you for your very excellent data and feedback from you. car dealers san jose 17274

  7. 336967 744357extremely nice post, i definitely love this web site, keep on it 90073

Leave a comment

Your email address will not be published.